Válogatott publikációk (2018)

Danciu C, Muntean D, Alexa E, Farcas C, Oprean C, Zupko I, Bor A, Minda D, Proks M, Buda V, Hancianu M, Cioanca O, Soica C, Popescu S, Dehelean CA: Phytochemical Characterization and Evaluation of the Antimicrobial, Antiproliferative and Pro-Apoptotic Potential of Ephedra alata Decne. Hydroalcoholic Extract against the MCF-7 Breast Cancer Cell Line. Molecules 24: 13 (2018) doi: 10.3390/molecules24010013


Danciu C, Zupko I, Bor A, Schwiebs A, Radeke H, Hancianu M, Cioanca O, Alexa E, Oprean C, Bojin F, Soica C, Paunescu V, Dehelean CA: Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts against A375 Human Melanoma and Dendritic Cells. Int J Mol Sci 19: 3624 (2018) doi: 10.3390/ijms19113624


    Fröhlich T, Kiss A, Wölfling J, Mernyák E, Kulmány ÁE, Minorics R, Zupkó I, Leidenberger M, Friedrich O, Kappes B, Hahn F, Marschall M, Schneider G, Tsogoeva SB: Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer. ACS Med Chem Lett 9: 1128-1133 (2018) doi: 10.1021/acsmedchemlett.8b00381


      Le TM, Bérdi P, Zupkó I, Fülöp F, Szakonyi Z: Synthesis and Transformation of (-)-Isopulegol-Based Chiral β-Aminolactones and β-Aminoamides. Int J Mol Sci 19: 3522 (2018) doi: 10.3390/ijms19113522


        Fröhlich T, Kiss A, Wölfling J, Mernyák E, Kulmány ÁE, Minorics R, Zupkó I, Leidenberger M, Friedrich O, Kappes B, Hahn F, Marschall M, Schneider G, Tsogoeva SB. Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer. ACS Med Chem Lett. 9:1128-1133 (2018) doi: 10.1021/acsmedchemlett.8b00381


          Csányi A, Hajagos-Tóth J, Kothencz A, Gaspar R, Ducza E. Effects of different antibiotics on the uterine contraction and the expression of aquaporin 5 in term pregnant rat. Reprod Toxicol. 81:64-70. (2018) doi: 10.1016/j.reprotox.2018.07.082


            Szűcs KF, Grosz G, Süle M, Sztojkov-Ivanov A, Ducza E, Márki A, Kothencz A, Balogh L, Gáspár R. Detection of stress and the effects of central nervous system depressants by gastrointestinal smooth muscle electromyography in wakeful rats. Life Sci. 205:1-8. (2018) doi: 10.1016/j.lfs.2018.05.015


              Mótyán G, Mérai L, Kiss MA, Schelz Z, Sinka I, Zupkó I, Frank É. Microwave-assisted synthesis of biologically relevant steroidal 17-exo-pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence. Beilstein J Org Chem. 14:2589-2596. (2018) doi: 10.3762/bjoc.14.236


                Sinka I, Kiss A, Mernyák E, Wölfling J, Schneider G, Ocsovszki I, Kuo CY, Wang HC, Zupkó I. Antiproliferative and antimetastatic properties of 3-benzyloxy-16-hydroxymethylene-estradiol analogs against breast cancer cell lines. Eur J Pharm Sci. 123:362-370. (2018) doi: 10.1016/j.ejps.2018.07.029


                  Kırmızıbekmez H, Kúsz N, Bérdi P, Zupkó I, Hohmann J. New iridoids from the roots of Valeriana dioscoridis Sm. Fitoterapia. 130:73-78. (2018) doi: 10.1016/j.fitote.2018.08.007


                    Bús C, Kúsz N, Jakab G, Senobar Tahaei SA, Zupkó I, Endrész V, Bogdanov A, Burián K, Csupor-Löffler B, Hohmann J, Vasas A. Phenanthrenes from Juncus Compressus Jacq. with Promising Antiproliferative and Anti-HSV-2 Activities. Molecules. 23(8). (2018) doi: 10.3390/molecules23082085

                      Kovacs B, Béni Z, Dékány M, Bózsity N, Zupko I, Hohmann J, Vanyolos A. Isolation and Structure Determination of Antiproliferative Secondary Metabolites from the Potato Earthball Mushroom, Scleroderma bovista (Agaricomycetes). Int J Med Mushrooms. 20(5):411-418. (2018) doi: 10.1615/IntJMedMushrooms.2018026043

                        Vollár M, Gyovai A, Szűcs P, Zupkó I, Marschall M, Csupor-Löffler B, Bérdi P, Vecsernyés A, Csorba A, Liktor-Busa E, Urbán E, Csupor D. Antiproliferative and Antimicrobial Activities of Selected Bryophytes. Molecules. 23(7). (2018) doi: 10.3390/molecules23071520

                          Kiss A, Mernyák E, Wölfling J, Sinka I, Zupkó I, Schneider G. Stereoselective synthesis of the four 16-hydroxymethyl-3-methoxy- and 16-hydroxymethyl-3-benzyloxy-13α-estra-1,3,5(10)-trien-17-ol isomers and their antiproliferative activities. Steroids. 134:67-77. (2018) doi: 10.1016/j.steroids.2018.02.008

                            Vágvölgyi M, Martins A, Kulmány Á, Zupkó I, Gáti T, Simon A, Tóth G, Hunyadi A. Nitrogen-containing ecdysteroid derivatives vs. multi-drug resistance in cancer: Preparation and antitumor activity of oximes, oxime ethers and a lactam. Eur J Med Chem. 144:730-739. (2018) doi: 10.1016/j.ejmech.2017.12.032


                              Gyovai A, Minorics R, Kiss A, Mernyák E, Schneider G, Szekeres A, Kerekes E, Ocsovszki I, Zupkó I. Antiproliferative Properties of Newly Synthesized 19-Nortestosterone Analogs Without Substantial Androgenic Activity. Front Pharmacol. 9:825. (2018) doi: 10.3389/fphar.2018.00825


                                Minorics R, Zupko I. Steroidal Anticancer Agents: An Overview of Estradiol-related Compounds. Anticancer Agents Med Chem. 18(5):652-666. (2018) doi: 10.2174/1871520617666171114111721


                                  Szűcs KF, Grosz G, Süle M, Sztojkov-Ivanov A, Ducza E, Márki A, Kothencz A, Balogh L, Gáspár R. Detection of stress and the effects of central nervous system depressants by gastrointestinal smooth muscle electromyography in wakeful rats. Life Sci. 205:1-8. (2018) doi: 10.1016/j.lfs.2018.05.015

                                    Bartos C, Ambrus R, Kovács A, Gáspár R, Sztojkov-Ivanov A, Márki Á, Janáky T, Tömösi F, Kecskeméti G, Szabó-Révész P. Investigation of Absorption Routes of Meloxicam and Its Salt Form from Intranasal Delivery Systems. Molecules. 23(4). (2018) doi: 10.3390/molecules23040784

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