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Research & Research Groups

Research - TEAM #4

Team 4

Team leader: Prof. Dr. Piroska Szabó-Révész
revesz
@pharm.u-szeged.hu

 

Research topic: Particle engineering. Nanotechnology-Nanomedicine. 

Nanosized drug delivery systems, Drug delivery across artificial and biological barriers

·          Particle engineering
- different preparation methods for particle size reduction (top down, bottom-up)
- micronization, nanonization and amorphization of drug crystals
-
physico-chemical and chemical studies of crystalline, semi-crystalline and amorphous materials ((XRPD, NIRS, DSC, TG-MS, FT-IR, RAMAN)
- quantitative analysis of crystallinity degree (XRPD, NIRS, DSC)

·               Nanotechnology-Nanomedicine
- development of nanocrystals and amorf-nanoparticles to improve the drug solubility
- development of nanosized drug delivery systems (nano-DDSs) for target therapy (liposomes, niosomes, nanocomposites, etc.)
 

 Drug delivery across artificial and biological barriers:
- in vitro, ex vivo and in vivo permeability studies
- studies of different systems/dosage forms with micro- and nanoparticles (liquid, semi-solid, solid)
- use of alternative administration routs (intranasal and pulmonary)  to reach the blood circulation

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